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A TREATMENT FOR ADULTS WITH TYPE 2 DIABETES MELLITUS, IN ADDITION TO DIET AND EXERCISE

Dosing & Administration

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CONVENIENT, ONCE-DAILY DOSING

 
 

ONCE-DAILY DOSING

 

5 mg

RECOMMENDED STARTING DOSE

 

10 mg

FOR ADDITIONAL A1C CONTROL

FARXIGA tablets shown are not actual sizes.

 
 

A.M. DOSING

 
 

WITH OR WITHOUT FOOD

  • In patients with volume depletion, correcting this condition prior to initiation of FARXIGA is recommended1
  • Monitoring glycemic control with urine glucose tests or 1,5-anhydroglucitol (1,5-AG) assay is not recommended in patients taking FARXIGA1
  • Acute Kidney Injury and Impairment in Renal Function: FARXIGA causes intravascular volume contraction and renal impairment, with reports of acute kidney injury requiring hospitalization and dialysis. Consider temporarily discontinuing in settings of reduced oral intake or fluid losses. If acute kidney injury occurs, discontinue and promptly treat.
  • FARXIGA increases serum creatinine and decreases eGFR. Elderly patients and patients with impaired renal function may be more susceptible to these changes. Before initiating FARXIGA, evaluate renal function and monitor periodically. FARXIGA is not recommended in patients with an eGFR persistently between 30 and <60 mL/min/1.73 m2

 

FOR PATIENTS WHO NEED A CHANGE

Consider FARXIGA for patients who:

Need improvement in A1C

  • 45% of patients with type 2 diabetes mellitus are still not achieving a goal of A1C <7%2,*

Could also benefit from weight and BP reductions

  • In adults, type 2 diabetes mellitus accounts for 90% to 95% of all diagnosed cases of diabetes3
    • 85% of adults with diagnosed diabetes are overweight or obese4
    • 71% have blood pressure ≥140/90 mm Hg or are taking antihypertensive medications3
 

FARXIGA is not indicated for weight loss or the treatment of hypertension.

*According to an NHANES survey from 2009-2010.

When added to metformin.

  • Hypotension: FARXIGA causes intravascular volume contraction, and symptomatic hypotension can occur. Assess and correct volume status before initiating FARXIGA in patients with impaired renal function, elderly patients, or patients on loop diuretics. Monitor for hypotension